Advances in Seizure Disorders

Seizures, seizure disorders and epilepsy cause a major disruption in the lives of our patients, yet are very amenable to treatment. Although many patients are refractrory to treatment, overall, most patients with epilepsy will do well since it is a potentially treatable neurologic disorder when managed properly.

The proper management of seizure disorders and epilepsy requires knowledge of the classification, differential diagnosis, evaluation and treatment of seizures and epilepsy and associated fields such as neurophysiology and neuroradiology. Seizures and epilepsy occur in all age groups (newborn, infant, child and adult), each group has specific characteristics, and management varies among groups.

There are various treatment modalities for epilepsy, including antiepileptic drugs (AEDs), epilepsy surgery, and various techniques for neurostimulation. The explosion in neuroscience, including basic neuroscience, developmental neurobiology, neurogenetics, and pharmacology and pharmacogenetics, has rapidly changed the field and requires that the physician and basic scientist constantly acquire and apply this knowledge.

Each volume in this series will review the basic science and clinical aspects applicable to a specific topic in seizures and epilepsy. This should allow the clinician to incorporate recent basic science advancements into the clinical care and optimize the care of their patients and for the neuroscientist to appreciate the clinical implication of their work.